For an unforgettable clubbing experience in Asunción, Velvet Asuncion stands out with its impressive capacity and top-notch events. Coyote Asuncion is another premier club, known for its large space and vibrant nightlife. Morgan Warehouse, Nightclub offers a unique atmosphere with its eclectic music and energetic crowd. Broadway is also a notable venue, providing a spacious dance floor and a variety of music genres to keep the party going all night.

Asunción is home to several popular local musicians who have made a significant impact on the music scene. Aye Alfonso is a standout artist known for her captivating performances and unique style. Kchiporros, a well-loved band, brings a lively mix of genres to their music, making them a favorite among fans. Los Verduleros and Tierra Adentro are also highly regarded, each bringing their own distinct sound and energy to the stage. These artists, among others, contribute to the rich musical tapestry of Asunción.

For those who enjoy outdoor live music, Asunción offers some fantastic spots. The Jockey Club del Paraguay is a prime location, hosting large-scale outdoor events and concerts. Puerto de Asuncion provides a scenic backdrop for live performances, making it a popular choice for music lovers. Espacio Idesa is another excellent venue, offering a unique outdoor setting for various music events. These spots, along with others, provide a great atmosphere for enjoying live music under the open sky.